"the Academy" also pointed out that exclusion of children from drug studies was more unethical than clinical testing, and could lead to devastating results.
The antibiotic chloramphenicol was released in the 1950s without adequate testing in infants and children. As use of the drug became more common, reports of a serious and often fatal reaction called the Grey Baby Syndrome surfaced. This reaction was related to slow clearance of the drug in infants as compared to adults, due to deficiency in hepatic glucuronyl transferase in infants. Similarly, though less devastating, widespread use of tetracycline in children was subsequently shown to be associated with dental dysplasia.
EXP Podcast #737: The Fallout TV Series Debrief
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*Just a typical day in the wasteland.*War never changes - the streaming
television war, that is! This week we do a deep dive on the new Fallout
series....
3 weeks ago
1 comment:
Wow,
so many posts, so little time. Interesting facts though. So how can they test drugs on kids? If you test it on humans you have the problem like the gene therapy trial. And if you don't you get this one?
no win - no win situation :-P
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